Return on Health is a podcast about longevity, prevention and the future of health — built on one rule: listen to every side, pressure-test every claim, and keep science and common sense at the center.
Biomedical gerontologist Aubrey de Grey on treating aging as damage that can be repaired, what his latest mouse study actually showed, and why he still thinks longevity escape velocity is within reach.
Why de Grey treats aging as damage that can be repaired rather than a process to slow. What his latest mouse rejuvenation study tested — and where the first one fell short. Plus longevity escape velocity, SENS versus the Hallmarks of Aging, and why he does not trust today's biological age clocks.
Every episode pressure-tests one question. Researchers, founders, clinicians, skeptics — then the data. Filter by topic, or start from the top.














Health content optimizes for clicks. We optimize for decisions you can actually make. Fewer claims, more context, honest uncertainty.
Researchers, founders, clinicians, skeptics, innovators — and we pressure-test their ideas. Some viewpoints align, some clash. That is the point.
Most systems wait until something breaks. Longevity, performance and prevention start decades earlier. We make that case, episode by episode.
When evidence is thin, we say so. When something works, we say so. Trends die fast; fundamentals compound. We stay with the fundamentals.
Niko and Miguel met during their Master's at NOVA SBE. Late-night debates about health, medicine and broken incentives turned into a shared frustration with the system — and, eventually, this podcast.
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